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The list of records Kylie holds at the Manchester venue is unprecedented.
The pop icon has performed more shows, and to more people, at the M.E.N Arena than at any other venue in the world.
More than 300,000 concertgoers have seen Kylie at the Arena since her 2002 debut with her sold-out summer 2008 shows confirming her position as the biggest selling solo artist in the history of the venue.
Kylie now returns to the city which she says "has always welcomed me so much" to perform tracks from her latest album Aphrodite - including current hit single Better Than Today - alongside hits from her back catalogue spanning over two decades.
John Knight, General Manager for the M.E.N Arena, said: "Manchester holds a very special place in its heart for Kylie and the feeling is more than mutual. She loves performing here and this year's shows are going to be one of the musical highlights of 2011.
"Since her first show with us nearly a decade ago Kylie's returned again and again with bigger and better shows and, after seeing the initial production plans for her new Les Folies shows, her Manchester fans are in for another breathtaking treat".
Devotion, a duet Kylie has recorded with Manchester synthpop duo The Hurts, is out now.
Price includes all ticketmaster booking fees.